Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
IL-29/IFN-lambda 1 Antibody [DyLight 350]
Novus Biologicals | Catalog # NBP2-99978UV
Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Polyclonal Rabbit IgG
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Product Specifications
Immunogen
Produced in rabbits immunized with purified, recombinant Human IL-29/IFN-lambda 1 (Accession#: NP_742152.1; Met1-Thr200)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Applications for IL-29/IFN-lambda 1 Antibody [DyLight 350]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen and protein A Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: IL-29/IFN-lambda 1
Long Name
Interleukin 29
Alternate Names
IFN-lambda 1, IL29
Gene Symbol
IFNL1
Additional IL-29/IFN-lambda 1 Products
Product Documents for IL-29/IFN-lambda 1 Antibody [DyLight 350]
Product Specific Notices for IL-29/IFN-lambda 1 Antibody [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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