Q: Is the Recombinant Canine Il-31 Protein (NBP2-59591) functional? As in, could it be used to stimulate canine cells in an assay?

A: Unfortunately, this canine Il-31 protein was manufactured for the purpose of a control for SDS-PAGE and possibly for western blot. It has not been tested for bioactivity.

Recombinant Canine IL-31 His Protein

Novus Biologicals | Catalog # NBP2-59591

(1)

Citations (2)

Product Documents

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

Baculovirus

Tag

His

Applications

SDS-PAGE

View all IL-31 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 24-159 of Canine IL-31

Source:Baculovirus

Amino Acid Sequence: SHMAPTHQLP PSDVRKIILE LQPLSRGLLE DYQKKETGVP ESNRTLLLCL TSDSQPPRLN SSAILPYFRA IRPLSDKNII DKIIEQLDKL KFQHEPETEI SVPADTFECK SFILTILQQF SACLESVFKS LNSGPQHHHH HH

Purity

>95%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1 microgram of protein (determined by LAL method)

Predicted Molecular Mass

16.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Reviewed Applications

Read 1 review rated 5 using NBP2-59591 in the following applications:

Immunoassay Standard (1 Review)

Scientific Data Images for Recombinant Canine IL-31 His Protein

SDS-PAGE: Recombinant Canine IL-31 His Protein [NBP2-59591]

SDS-Page: Recombinant Canine IL-31 Protein [NBP2-59591] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP2-59591

Formulation	PBS (pH 7.4), 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-31

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting ofIL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma(Dillon et al., 2004 (PubMed 15184896)).(supplied by OMIM)

Long Name

Interleukin 31

Alternate Names

IL31

Entrez Gene IDs

100302725 (Canine)

Gene Symbol

IL31

Additional IL-31 Products

Product Documents for Recombinant Canine IL-31 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Canine IL-31 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

IL-6 Family

Citations for Recombinant Canine IL-31 His Protein

Customer Reviews for Recombinant Canine IL-31 His Protein (1)

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Recombinant Canine IL-31 Protein

Name: Anonymous

Application: Immunoassay Standard

Verified Customer | Posted 10/02/2020

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