Interleukin 36 alpha (IL-36 alpha), also known as IL-1F6 and FIL1 epsilon, is a member of the IL-1 family of proteins. Cells reported to express IL-36 alpha include monocytes, B cells, and T cells. Notably, IL-36 alpha is the only novel IL-1 family member expressed on T-cells. The receptor for IL-36 alpha is reported to be a combination of IL-1 R6/IL-1 R rp2 and IL-1 R3/IL-1 R AcP. Recombinant IL-36 alpha has been shown to activate pathways involving NF-kappa B and MAPK in an IL-1 R6/IL-1 R rp2-dependent manner.
IL-36 alpha/IL-1F6 Antibody (C1) - BSA Free
Novus Biologicals | Catalog # NBP3-41659
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Key Product Details
Species Reactivity
Human, Rat, Porcine
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # C1
Format
BSA Free
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Product Specifications
Immunogen
Immunized with recombinant Human IL-36 alpha/IL-1F6 (Uniprot#: Q9UHA7; Met1-Phe158 (Uniprot#: Q9UHA7)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Scientific Data Images for IL-36 alpha/IL-1F6 Antibody (C1) - BSA Free
Western Blot: IL-36 alpha/IL-1F6 Antibody (C1) [NBP3-41659] -
Western Blot: IL-36 alpha/IL-1F6 Antibody (C1) [NBP3-41659] - Lane 1: Porcine Cerebrum lysate; Lane 2: Rat Cerebrum lysate; Lane 3: Human U87MG cell lysate; Primary Ab: 2ug/ml NBP3-41659; Second Ab: 0.2ug/mL HRP-conjugated Rabbit Anti-Mouse IgG Polyclonal AntibodyApplications for IL-36 alpha/IL-1F6 Antibody (C1) - BSA Free
Application
Recommended Usage
Western Blot
0.5-2ug/mL
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
0.01M PBS, pH7.4, 50% glycerol
Format
BSA Free
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: IL-36 alpha/IL-1F6
Long Name
Interleukin 36 alpha/Interleukin 1 Family 6
Alternate Names
FIL1 epsilon, IL-1E, IL1F6, IL36 alpha, IL36A
Gene Symbol
IL36A
Additional IL-36 alpha/IL-1F6 Products
Product Documents for IL-36 alpha/IL-1F6 Antibody (C1) - BSA Free
Certificate of Analysis
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Product Specific Notices for IL-36 alpha/IL-1F6 Antibody (C1) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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Associated Pathways
