ILT2/CD85j/LILRB1 Antibody

Novus Biologicals | Catalog # NBP2-15014

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all LILRB1/CD85j/ILT2 Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ILT2/CD85j/LILRB1. The exact sequence is proprietary.

Reactivity Notes

Rhesus Monkey (82%), Chimpanzee (88%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ILT2/CD85j/LILRB1 Antibody

Western Blot: ILT2/CD85j/LILRB1 Antibody [NBP2-15014]

Western Blot: ILT2/CD85j/LILRB1 Antibody [NBP2-15014]

Western Blot: ILT2/CD85j/LILRB1 Antibody [NBP2-15014] - Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE; antibody diluted at 1:10000.
ILT2/CD85j/LILRB1 Antibody

Immunocytochemistry/ Immunofluorescence: ILT2/CD85j/LILRB1 Antibody [NBP2-15014] -

LILRB1 antibody [N1C1] detects LILRB1 protein by immunofluorescent analysis.
Sample: NK-92 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: LILRB1 stained by LILRB1 antibody [N1C1] (NBP2-15014) diluted at 1:100.
Blue: Fluoroshield with DAPI.
ILT2/CD85j/LILRB1 Antibody

Western Blot: ILT2/CD85j/LILRB1 Antibody [NBP2-15014] -

Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with LILRB1 antibody [N1C1] (NBP2-15014) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for ILT2/CD85j/LILRB1 Antibody

Application
Recommended Usage

Western Blot

1:5000-1:20000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LILRB1/CD85j/ILT2

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 1

Alternate Names

CD85j, ILT2, LIR1, MIR7

Gene Symbol

LILRB1

UniProt

Q8NHL6

Additional LILRB1/CD85j/ILT2 Products

Product Documents for ILT2/CD85j/LILRB1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for ILT2/CD85j/LILRB1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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