Importin 11 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-49505

Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Importin 11 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QLLGNMIEMWVDRMDNITQPERRKLSALALLSLLPSDNSVIQDKFCGIINISVEGLHDVMTEDPETGTYKDCMLMSHLEEPKVTEDEEPPTEQD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Importin 11 Antibody - BSA Free

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505] - Analysis in human testis and skeletal muscle tissues. Corresponding RNA-seq data are presented for the same tissues.
Western Blot: Importin 11 Antibody [NBP2-49505]

Western Blot: Importin 11 Antibody [NBP2-49505]

Western Blot: Importin 11 Antibody [NBP2-49505] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10Lane 2: Human cell line RT-4 Lane 3: Human cell line U-251 MG
Immunocytochemistry/ Immunofluorescence: Importin 11 Antibody [NBP2-49505]

Immunocytochemistry/ Immunofluorescence: Importin 11 Antibody [NBP2-49505]

Immunocytochemistry/Immunofluorescence: Importin 11 Antibody [NBP2-49505] - Staining of human cell line CACO-2 shows localization to nucleus & nucleoli fibrillar center. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505] - Staining of human testis shows moderate cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505]

Immunohistochemistry-Paraffin: Importin 11 Antibody [NBP2-49505] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.

Applications for Importin 11 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Importin 11

Principal Names: Importin-11 (IPO11); Imp11; Ran-binding protein 11 (RanBP11); Official Gene Symbol: IPO11 Gene ID: 51194 (Human) Gene Map Locus: 5q12.1 (Human) Importin-11 is a novel member of Karyopherin family. Karyopherins are transport receptors that mediate the transport of protein and RNA across the nucleus and cytoplasm. Importin-11 consists of an N-terminal Ran-binding domain, a central cargo-binding region and C-terminal region. It interacts with Ran-GTPase and constitutively shuttles between the nucleus and cytoplasm. Reports suggest Importin-11 primarily mediates the transport of ribosomal protein L12 and UbcM2, an E2 ubiquitin-conjugating enzyme.

Alternate Names

Imp11, importin 11, Ran binding protein 11, Ran-binding protein 11, RANBP11, RanBP11importin-11, SLRN

Gene Symbol

IPO11

Additional Importin 11 Products

Product Documents for Importin 11 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Importin 11 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Importin 11 Antibody - BSA Free

Customer Reviews for Importin 11 Antibody - BSA Free

There are currently no reviews for this product. Be the first to review Importin 11 Antibody - BSA Free and earn rewards!

Have you used Importin 11 Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies