Inhibin alpha Antibody (rINHA/6919)

Novus Biologicals | Catalog # NBP3-48910

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # rINHA/6919 expressed in HEK293
View all Inhibin A Primary Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human Inhibin alpha protein (around aa 233-362) (exact sequence is proprietary) (Uniprot: P05111)

Localization

Secreted

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Scientific Data Images for Inhibin alpha Antibody (rINHA/6919)

Inhibin alpha Antibody (rINHA/6919)

Immunohistochemistry-Paraffin: Inhibin alpha Antibody (rINHA/6919) [NBP3-48910] -

IHC analysis of formalin-fixed, paraffin-embedded human testicular carcinoma. Staining with Inhibin alpha Antibody (rINHA/6919) at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
Inhibin alpha Antibody (rINHA/6919)

Immunohistochemistry-Paraffin: Inhibin alpha Antibody (rINHA/6919) [NBP3-48910] -

IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control using Inhibin alpha Antibody (rINHA/6919)at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
Inhibin alpha Antibody (rINHA/6919)

Western Blot: Inhibin alpha Antibody (rINHA/6919) [NBP3-48910] -

Western blot analysis of human testis tissue lysate using Inhibin alpha Antibody (rINHA/6919).

Applications for Inhibin alpha Antibody (rINHA/6919)

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Inhibin A

INHA(A-inhibin subunit precursor, inhibin alpha subunit ),also called inhibin(alpha),which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.

Alternate Names

INHA, Inhibin A

Gene Symbol

INHA

Additional Inhibin A Products

Product Documents for Inhibin alpha Antibody (rINHA/6919)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Inhibin alpha Antibody (rINHA/6919)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Activin Family

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Protocols

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FAQs

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