Integrin alpha 2/CD49b Antibody (430907) [FITC]

Name: Integrin alpha 2/CD49b Antibody (430907) [FITC]
Brand: Novus Biologicals
SKU: FAB12331F
Price: 529 USD
Availability: InStock

Novus Biologicals | Catalog # FAB12331F

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Rat IgG_2A Clone # 430907

View all Integrin alpha 2/CD49b Primary Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Integrin alpha 2/CD49b
Tyr30-Thr1132
Accession # P17301

Specificity

Detects human Integrin alpha 2/CD49b in direct ELISAs and Western blots. In direct ELISAs and Western blots, 50‑100% cross‑reactivity with recombinant mouse (rm) Integrin alpha 2 is observed and no cross-reactivity with recombinant human (rh) Integrin alpha 1, alpha 3, alpha 5, alpha 6, alpha 8, alpha 9, alpha 10, alpha 11, alpha L, alpha M, or alpha V is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG_2A

Applications for Integrin alpha 2/CD49b Antibody (430907) [FITC]

Application

Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Alternate Names

CD49b, ITGA2, VLA-2 alpha

Gene Symbol

ITGA2

Additional Integrin alpha 2/CD49b Products

Product Documents for Integrin alpha 2/CD49b Antibody (430907) [FITC]

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Certificate of Analysis

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Product Specific Notices for Integrin alpha 2/CD49b Antibody (430907) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.