Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin/Cy7 (Excitation = 650;755 nm, Emission = 767 nm)

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # Hu117
View all Integrin alpha 4 beta 7/LPAM-1 Primary Antibodies »

Product Specifications

Immunogen

Human Integrin alpha 4 beta 7/LPAM‑1

Specificity

Detects human Integrin alpha 4 beta 7/LPAM‑1 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Vedolizumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7]

Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7]

Detection of Integrin alpha 4 beta 7/LPAM‑1 in Human NK Cells by Flow Cytometry.

NK cells were isolated and stained at RT for 20min with anti-alpha 4 beta 7/LPAM‑1 conjugated with APC-Cy7 (left) or isotype control (right). Image from a verified customer review.

Applications for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Reviewed Applications

Read 1 review rated 5 using FAB10078APCCY7 in the following applications:

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Spectra Viewer

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Advanced Features

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7]

Cy is a registered trademark of Global Life Sciences Solutions Germany GmbH.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7] (1)

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Customer Images

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  • Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7]
    Name: Luis Romero Martin
    Application: Flow Cytometry
    Sample Tested: Natural killer cells
    Species: Human
    Verified Customer | Posted 04/03/2025
    NK cells were isolated and stained at RT for 20min with anti-Integrin alpha4beta7 conjugated with APC-Cy7 (left) or isotype control (right).
    Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Allophycocyanin/Cy7] FAB10078APCCY7

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