Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu143) [Janelia Fluor® 646]

Name: Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu143) [Janelia Fluor® 646]
Brand: Novus Biologicals
SKU: FAB10548J
Price: 539 USD
Availability: InStock

Novus Biologicals | Catalog # FAB10548J

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Product Documents

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Product Specifications
Applications
Spectra Viewer
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, CyTOF-ready

Label

Janelia Fluor 646

Antibody Source

Monoclonal Human IgG₁ Clone # Hu143

View all Integrin alpha 4 beta 7/LPAM-1 Primary Antibodies »

Product Specifications

Immunogen

Human Integrin alpha4 beta7

Specificity

Detects Human Integrin alpha 4 beta 7/LPAM‑1 in direct ELISAs.This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Abrilumab. This product is for research use only.

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Applications for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu143) [Janelia Fluor® 646]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Flow Cytometry Panel Builder

Bio-Techne Knows Flow Cytometry

Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

Build Your Panel Now

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha 4 beta 7/LPAM-1

The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)

Alternate Names

CD49d/beta7, LPAM-1, LPAM1

Gene Symbol

ITGA4

Additional Integrin alpha 4 beta 7/LPAM-1 Products

Product Documents for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu143) [Janelia Fluor® 646]

Download Product Datasheets

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Product Specific Notices for Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu143) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.