Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

Name: Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]
Brand: Novus Biologicals
SKU: NBP1-97568
Price: 459 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-97568

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Product Documents

Clone Ber-ACT8 was used by HLDA to establish CD designation.

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Product Specifications
Scientific Data
Applications
Spectra Viewer
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Primate

Applications

Flow Cytometry

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # Ber-ACT8

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Product Specifications

Immunogen

HTLV-1 induced human T cell line MAPS16

Specificity

The mouse monoclonal antibody Ber-ACT8 recognizes an extracellular epitope of CD103 (alpha E integrin), a type I transmembrane glycoprotein primarily found on intestinal intraepithelial lymphocytes. HLDA V; WS Code A067

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Scientific Data Images for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

Flow Cytometry: Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC] [NBP1-97568] - Surface staining of CD103 on PHA-activated PBMC with anti-CD103 (Ber-ACT8) FITC.

Applications for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

Application

Recommended Usage

Flow Cytometry

4ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

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Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

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Formulation, Preparation, and Storage

Purification

Size Exclusion Chromatography

Formulation

Phosphate buffered saline (PBS), pH 7.4

Preservative

15mM Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha E/CD103

CD103 / Integrin alphaE is an integrin subunit that is expressed on intraepithelial lymphocytes, epithelial dendritic cells, lamina propria-derived dendritic cells, a subpopulation of lamina propria T cells, a small subset of peripheral lymphocytes, namely T reg cells, and on activated and TGF-beta stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin beta7 subunit to form alphaE/beta7 integrin (mucosal lymphocyte 1 antigen), which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium, and, in addition to the role in adhesion, may serve as an accessory molecule for intraepithelial lymphocyte activat

Alternate Names

CD103, HUMINAE, ITGAE

Gene Symbol

ITGAE

Additional Integrin alpha E/CD103 Products

Product Documents for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

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Certificate of Analysis

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Product Specific Notices for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.