Integrin beta 7 Antibody (2G18) - Azide and BSA Free

Novus Biologicals | Catalog # NB110-94147

Novus Biologicals
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Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Flow Cytometry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2 Clone # 2G18

Format

Azide and BSA Free
View all Integrin beta 7 Primary Antibodies »

Product Specifications

Immunogen

Cell lysates of mouse lymphocytes

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Scientific Data Images for Integrin beta 7 Antibody (2G18) - Azide and BSA Free

Immunohistochemistry: Integrin beta 7 Antibody (2G18) - Azide and BSA Free [NB110-94147]

Immunohistochemistry: Integrin beta 7 Antibody (2G18) - Azide and BSA Free [NB110-94147]

Immunohistochemistry: Integrin beta 7 Antibody (2G18) [NB110-94147] - LPAM-1 immunohistochemistry staining of paraffin sections of mouse spleen from LPS exposed animals.

Applications for Integrin beta 7 Antibody (2G18) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:50-1:200

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:100-200

Immunoprecipitation

1:100-1:400

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.4 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Integrin beta 7

Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. This antibody has been shown to be useful for studies of the induction of homotypic cellular aggregation and the blockade of binding to cell adhesion molecules.

Alternate Names

ITGB7

Entrez Gene IDs

16401 (Mouse)

Gene Symbol

ITGA4

Additional Integrin beta 7 Products

Product Documents for Integrin beta 7 Antibody (2G18) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for Integrin beta 7 Antibody (2G18) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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