IQCB1 Antibody - Azide and BSA Free

Novus Biologicals | Catalog # H00009657-B01P

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Format

Azide and BSA Free
View all IQCB1 Primary Antibodies »

Product Specifications

Immunogen

IQCB1 (NP_001018865, 1 a.a. - 465 a.a.) full-length human protein. MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSSELKKIKQDIYCYDLIQYCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGRQLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELIQNVLQSDHFLHLLQADNVQIGSAVMMMLQNILQINRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKYRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEESGDEIDVPKDELSIELENLFIGGTKPP

Specificity

IQCB1 - IQ motif containing B1,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for IQCB1 Antibody - Azide and BSA Free

Western Blot: IQCB1 Antibody [H00009657-B01P]

Western Blot: IQCB1 Antibody [H00009657-B01P]

Western Blot: IQCB1 Antibody [H00009657-B01P] - Analysis of IQCB1 expression in transfected 293T cell line by IQCB1 polyclonal antibody. Lane 1: IQCB1 transfected lysate(51.15 KDa). Lane 2: Non-transfected lysate.

Applications for IQCB1 Antibody - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IQCB1

CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes. CEP290 is ubiquitously expressed; strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5) [MIM:610188], Senior-Loken syndrome type 6 (SLSN6) [MIM:610189], Leber congenital amaurosis type 10 (LCA10) [MIM:611755] and Meckel syndrome type 4 (MKS4) [MIM:611134]. Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.

Alternate Names

IQ calmodulin-binding motif containing 1, IQ motif containing B1, KIAA0036nephrocystin 5, Nephrocystin-5, NPHP5IQ calmodulin-binding motif-containing protein 1, p53 and DNA damage-regulated IQ motif protein, PIQ, SLSN5

Entrez Gene IDs

9657 (Human)

Gene Symbol

IQCB1

UniProt

NP_001018865 (Human)

Additional IQCB1 Products

Product Documents for IQCB1 Antibody - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for IQCB1 Antibody - Azide and BSA Free

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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