Isradipine

Catalog # Availability Size / Price Qty
2004/10
2004/50
Isradipine | CAS No. 75695-93-1 | Cav1.x Channel Blockers
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Description: CaV1.x blocker
Alternative Names: PN 200-110

Chemical Name: 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid methyl 1-methylethyl ester

Purity: ≥99%

Product Details
Citations (6)
Reviews

Biological Activity

Potent and selective L-type voltage-gated Ca2+ channel blocker. EC50 and pA2 values are 1.4 nM and 10.3 for relaxation of depolarization- and Ca2+-induced contractions of rabbit aorta respectively; EC25 = 0.45 nM for reduction in rate of spontaneously beating guinea pig right atria. Long-acting antihypertensive agent in vivo, exerting primary effects on vascular tissue with secondary negative chronotropic action.

Technical Data

M.Wt:
371.39
Formula:
C19H21N3O5
Solubility:
Soluble to 50 mM in DMSO and to 20 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
75695-93-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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