ISX 9

Catalog # Availability Size / Price Qty
4439/10
4439/50
Cat.No. 4439 - ISX 9 | C11H10N2O2S | CAS No. 832115-62-5
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Description: Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

Chemical Name: N-Cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Neurogenic agent. Mediates neuroD reporter gene induction via activation of Ca2+ influx; increases expression of neurogenic differentiation 1 (NeuroD1) transcription factor. Induces neuronal differentiation in human cortical neuronal cells (HCN), adult mouse whole brain (MWB) and subventricular zone (SVZ) progenitors. Also shown to induce cardiomyogenic differentiation of Notch-activated epicardium-derived cells in vitro.

Technical Data

M.Wt:
234.27
Formula:
C11H10N2O2S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
832115-62-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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Citation for ISX 9

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