(±)-J 113397

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(±)-J 113397 | CAS No. 217461-40-0 | NOP Receptor Antagonists
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Description: Potent and selective NOP antagonist

Chemical Name: (±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Potent and selective NOP receptor antagonist (IC50 values are 2.3, 1400, 2200 and > 10000 nM for NOP, κ, μ and δ-opioid receptors respectively). Inhibits nociceptin/orphanin FQ-induced hyperalgesia in the mouse tail-flick test.

Technical Data

M.Wt:
399.57
Formula:
C24H37N3O2
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
217461-40-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for (±)-J 113397

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