Key Product Details

Species Reactivity

Human

Applications

Neutralization

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 188323
View all Jagged 1 Primary Antibodies »

Product Specifications

Immunogen

NS0-derived recombinant human Jagged 1
Ser32-Asp296
Accession # P78504

Specificity

Detects human Jagged 1 in direct ELISAs. In direct ELISAs, approximately 50% cross‑reactivity with recombinant human Jagged 2 and recombinant rat Jagged 1 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Jagged 1 Antibody (188323) [Dylight 350]

Application
Recommended Usage

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Jagged 1

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is theligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations thatalter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play arole in hematopoiesis. (provided by RefSeq)

Alternate Names

CD339, JAG1

Gene Symbol

JAG1

Additional Jagged 1 Products

Product Documents for Jagged 1 Antibody (188323) [Dylight 350]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Jagged 1 Antibody (188323) [Dylight 350]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers
Notch Pathway

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FAQs

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