Chemical Name: N-(2,6-Dimethylbenzoyl)-O-[3-(2-pyridinylamino)propyl]-L-tyrosine
Biological ActivityK34c is a potent and selective α5β1 integrin inhibitor (IC50 = 3.1 nM). K34c inhibits cell survival and migration, inhibits p53-dependent senescence induced by Temozolomide (Cat. No. 2706) or Ellipticine (Cat. No. 3357) and promotes apoptosis in U87MG cells. K34c also prevents TGFβ-induced infiltration in vivo and reduces cell adhesion on fibronectin.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
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