Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-49439

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # KLK3/2871R

Format

Azide and BSA Free
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Product Specifications

Immunogen

Recombinant full-length human KLK3 protein (Uniprot: P07288)

Localization

Secreted

Specificity

Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This antibody is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This antibody makes an excellent pair with clone A67-B/E3 for PSA tests.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Description

Prepared in 10mM PBS WITHOUT BSA & azide at 1.0mg/ml. Also available with 0.05% BSA & 0.05% azide.

Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous.

Scientific Data Images for Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free

Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free

Immunohistochemistry-Paraffin: Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free [NBP3-49439] -

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free.
Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free

Immunohistochemistry-Paraffin: Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free [NBP3-49439] -

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free.

Applications for Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: Kallikrein 3/PSA

PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liverderived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Alternate Names

KLK3, PSA

Gene Symbol

KLK3

Additional Kallikrein 3/PSA Products

Product Documents for Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for Kallikrein 3/PSA Antibody (KLK3/2871R) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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