Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

Kirrel3 antibody was raised against a 19 amino acid peptide near the amino terminus of human Kirrel3. The immunogen is located within amino acids 20 - 70 of Kirrel3. Amino Acid Squence: MAKDKFRRMNEGQVYSFSQ

Reactivity Notes

0

Specificity

Kirrel3/NEPH2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. Kirrel3/NEPH2 antibody is predicted to not cross-react with other members of the KIRREL protein family.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Kirrel3/NEPH2 Antibody [Biotin]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Kirrel3/NEPH2

NEPH2 is a member of the nephrin-like protein family, which includes NEPH1 (KIRREL; MIM 607428) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM]

Long Name

Kin of Irregular Chiasm-like 3

Alternate Names

KIRRE, mKIRRE, NEPH2

Gene Symbol

KIRREL3

Additional Kirrel3/NEPH2 Products

Product Documents for Kirrel3/NEPH2 Antibody [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Kirrel3/NEPH2 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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