Kisspeptin 10 (human)

Catalog # Availability Size / Price Qty
2570/1
Kisspeptin 10 (human)
1 Image
Description: Endogenous ligand for kisspeptin receptor
Alternative Names: Metastin (45-54), Kp-10
Product Details
Citations (5)
Supplemental Products
Reviews

Biological Activity

Potent endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.59 and 2.33 nM respectively. Inhibits metastasis and invasion in mouse melanomas and stimulates gonadotropin secretion following i.c.v. administration.

Analog also available.

Technical Data

M.Wt:
1302.45
Formula:
C63H83N17O14
Sequence:
YNWNSFGLRF

(Modifications: Phe-10 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
374675-21-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.
    Kotani et al.
    J.Biol.Chem., 2001;276:34631
  2. Kisspeptin acts directly and indirectly to increase GnRH neuron activity and its effects are modulated by OE.
    Peilecka-Fortuna et al.
    Endocrinology, 2007;149:1979
  3. Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumour cells through a specific transcriptional program not shared by other Gq-coupled receptors.
    Becker et al.
    Biochem.Biophys.Res.Comm., 2005;326:677

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for Kisspeptin 10 (human)

The citations listed below are publications that use Tocris products. Selected citations for Kisspeptin 10 (human) include:

5 Citations: Showing 1 - 5

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for Kisspeptin 10 (human)

There are currently no reviews for this product. Be the first to review Kisspeptin 10 (human) and earn rewards!

Have you used Kisspeptin 10 (human)?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.