Kisspeptin 10 (human)

  ( 5 citations )    
Product Datasheet
Catalog Number:2570
Alternate Names:Metastin (45-54), Kp-10
Chemical Name:
Product Details
Citations (5)
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Biological Activity
Potent endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.59 and 2.33 nM respectively. Inhibits metastasis and invasion in mouse melanomas and stimulates gonadotropin secretion following i.c.v. administration.

Analog also available.

Technical Data
  • M.Wt:
    1302.45
  • Formula:
    C63H83N17O14
  • Sequence:
    YNWNSFGLRF

    (Modifications: Phe-10 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    374675-21-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Kisspeptin 10 (human) include:

5 Citations: Showing 1 - 5
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  1. Galanin Activates G Protein Gated Inwardly Rectifying Potassium Channels and Suppresses Kisspeptin-10 Activation of GnRH Neurons.
    Authors: Constantin and Wray
    Endocrinology  2016;157:3197
  2. Differential stimulation of insulin secretion by GLP-1 and Kisspeptin-10.
    Authors: Schwetz Et al.
    PLoS One  2014;9:e113020
  3. Implication of metastasis suppressor gene, Kiss-1 and its receptor Kiss-1R in colorectal cancer.
    Authors: Ji Et al.
    Autophagy  2014;14:723
  4. Kisspeptin-10 enhanced egg production in quails associated with the increase of triglyceride synthesis in liver.
    Authors: Wu Et al.
    Asian-Australas J Anim Sci  2013;26:1080
  5. Effects of kisspeptin-10 on lipid metabolism in cultured chicken hepatocytes.
    Authors: Wu Et al.
    Asian-Australas J Anim Sci  2012;25:1229

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