Human KiSS1R/GRP54 (AAK83235) VersaClone cDNA

R&D Systems | Catalog # RDC0263

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Key Product Details

Species

Human

Accession Number

AAK83235

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: KiSS1R/GPR54

GPR54 is a Metastin Receptor. Metastin, also known as KiSS-1, is a metastasis suppressor gene. Mutations in GPR54 have been shown to cause autosomal recessive idiopathic hypogonadotropic hypogonadism in humans and mice, suggesting that GPR54 is a key regulator for the onset of puberty (Seminara et al. 2003). GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.

Long Name

KISS1 Receptor

Alternate Names

AXOR12, GPR54, Hypogonadotropin-1, Metastin Receptor, OT7T175

Entrez Gene IDs

84634 (Human); 114229 (Mouse); 78976 (Rat)

Gene Symbol

KISS1R

UniProt

AAK83235

Additional KiSS1R/GPR54 Products

Product Documents for Human KiSS1R/GRP54 (AAK83235) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human KiSS1R/GRP54 (AAK83235) VersaClone cDNA

For research use only

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