Selective inhibitor of protein kinase G (Ki
values are 0.23, 4 and > 10 μ
M for inhibition of PKG, PKC and PKA respectively). Inhibits SNP-stimulated PKG activity with an IC50
of 60 nM in dispersed smooth muscle cells and has little effect on PKA activity at concentrations of up to 10 μ
Soluble to 50 mM in DMSO
Desiccate at -20°C
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All Tocris products are intended for laboratory research use only.
The citations listed below are publications that use Tocris products. Selected citations for KT 5823 include:
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