LASS1 Antibody

Novus Biologicals | Catalog # NBP1-28480

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Predicted:

Bovine (100%), Mouse (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Western Blot, Peptide ELISA

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all LASS1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KDLREYDTAEAQ corresponding to internal region according to NP_937850.1.

Epitope

C terminus

Specificity

This antibody is expected to recognize both reported isoforms (NP_067090.1and NP_937850.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LASS1 Antibody

Western Blot: LASS1 Antibody [NBP1-28480]

Western Blot: LASS1 Antibody [NBP1-28480]

Western Blot: LASS1 Antibody [NBP1-28480] - Staining of Frontal Cortex lysate (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence.

Applications for LASS1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

1 - 3 ug/mL
Application Notes
WB: Approx. 37 kDa band observed in human brain (cerebellum, cerebral cortex and frontal cortex) lysates (calculated MW of 38.0 kDa band according to NP_937850.1). An additional band of unknown identity was also consistently observed at 85 kDa. This band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: LASS1

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.

Alternate Names

CerS1, LAG1 homolog, ceramide synthase 1, LAG1 longevity assurance homolog 1, LAG1MGC90349, longevity assurance (LAG1, S. cerevisiae) homolog 1, Longevity assurance gene 1 protein homolog 1, Protein UOG-1, UOG1LAG1 longevity assurance homolog 1 (S. cerevisiae), upstream of GDF1

Entrez Gene IDs

10715 (Human); 93898 (Mouse); 306351 (Rat)

Gene Symbol

CERS1

UniProt

P27544 (Human)

Additional LASS1 Products

Product Documents for LASS1 Antibody

Certificate of Analysis

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Product Specific Notices for LASS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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