[Leu31,Pro34]-Neuropeptide Y (human, rat)

Tocris Bioscience | Catalog # 1176

NPY Y1 receptor agonist
Tocris Bioscience

Key Product Details

Description

NPY Y1 receptor agonist

Alternative Names

[Leu31,Pro34]-NPY (human)
View all NPY Receptor Agonists »

Product Description

[Leu31,Pro34]-Neuropeptide Y (human, rat) is a high affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.

Product Specifications for [Leu31,Pro34]-Neuropeptide Y (human, rat)

Molecular Weight

4241.00

Formula

C189H284N54O56S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

132699-73-1

PubChem ID

24868223

InChI Key

MPWANDCMSKOYBR-MJWITIMHSA-N

SMILES

[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 19 publications citing the usage of this product.

Product Documents for [Leu31,Pro34]-Neuropeptide Y (human, rat)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for [Leu31,Pro34]-Neuropeptide Y (human, rat)

For research use only

Related Research Areas

Nutrition and Appetite
Obesity

Citations for [Leu31,Pro34]-Neuropeptide Y (human, rat)

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  • [Leu31,Pro34]-Neuropeptide Y current in spinal dorsal horn neuron
    Name: Allen Dickie
    Species: Mouse
    Assay Type: Ex Vivo
    Verified Customer | Posted 03/24/2023
    Whole cell patch clamp recording (voltage clamp) from spinal dorsal horn interneuron, in ex vivo slice preparation, in response to bath application of [Leu31,Pro34]-Neuropeptide Y (300 nM), in the presence of TTX, bicuculline and strychnine.
    [Leu31,Pro34]-Neuropeptide Y (human, rat) 1176

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