Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # B-T37

Format

Azide and BSA Free
View all LL-37 Primary Antibodies »

Product Specifications

Immunogen

Human antimicrobial peptide LL-37. Hybridoma: Myeloma X63/AG.8653 x Balb/c node cells

Specificity

Recognizes both natural and recombinant human LL-37

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for LL-37 Antibody (B-T37) - Azide and BSA Free

Flow Cytometry: LL-37 Antibody (B-T37) - Azide and BSA Free [NBP3-18120]

Flow Cytometry: LL-37 Antibody (B-T37) - Azide and BSA Free [NBP3-18120]

Flow Cytometry: LL-37 Antibody (B-T37) - Azide and BSA Free [NBP3-18120] - A typical intracytoplasmic staining profile with the B-T37 monoclonal antibody of granulocytes. The grey peak corresponds to the isotype control.

Applications for LL-37 Antibody (B-T37) - Azide and BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

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Advanced Features

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. Sterile-filtered through 0.22 um.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: LL-37

Cathelicidins are a family of antimicrobial proteins predominantly found in the peroxidase negative granules of neutrophils. The cathelicidins are synthesized as preproproteins. Within the neutrophils, they are stored in granules as inactive proforms after removal of the signal peptide. The active biologic domains of the cathelicidins generally reside in the C terminus. The C terminal antimicrobial peptides are activated when cleaved from the proforms of the cathelicidins by serine proteases from azurophil granules. FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in bone marrow and testis and neutrophils.

Alternate Names

18 kDa cationic antimicrobial protein, Antibacterial peptide FALL-39, CAP18, CAP-18, cathelicidin antimicrobial peptide, CRAMP, epididymis secretory sperm binding protein, FALL39, FALL-39, FALL-39 peptide antibiotic, hCAP-181, HSD26, LL37

Gene Symbol

CAMP

Additional LL-37 Products

Product Documents for LL-37 Antibody (B-T37) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for LL-37 Antibody (B-T37) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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