LRG1 Antibody (2F5.A2)

Novus Biologicals | Catalog # NBP1-51830

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunoassay

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 2F5.A2
View all LRG1 Primary Antibodies »

Product Specifications

Immunogen

Human LRG, covalently coupled to hemocyanin using glutaraldehyde

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for LRG1 Antibody (2F5.A2)

Application
Recommended Usage

Immunoassay

1 ug/ml
Application Notes
Antibody was used as detector for LRG on cytochrome C coated plates.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, containing 0.1% BSA

Preservative

0.02% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: LRG1

The monoclonal antibody recognizes leucine-rich alpha-2-glycoprotein (LRG), a member of the leucine-rich repeat family. LRG is a plasma protein of approximately 50 kDa. LRG consists of 312 amino acids. It has 1 galactosamine and 4 glucosamine oliogosacharides attached and has 2 intrachain disulfide bonds. Leucine comprises 66 of the 312 amino acids, and LRG contains at least eight 24-amino acid leucine-rich repeats. The consensus of these residues, termed leucine-rich repeats (LRR), has been identified as an LRR-containing domain. The primary function of LRRs is to provide versatile structural framework of the formation of protein-protein interactions. LRG is expressed during granulocyte differentiation. Although several family members of the leucine-rich repeat family have been shown to be involved in signal transduction, protein-protein interaction, or cell adhesion and development, a function for LRG remains elusive. LRG has been reported as a biomarker for certain diseases including microbial infections and cancer. LRG can be detected in human neutrophils and progenitor cells, but not in peripheral blood mononuclear cells. The monoclonal antibody 2F5.A2 can be used for immuno purification of human LRG.

Long Name

Leucine-rich alpha-2-glycoprotein 1

Alternate Names

HMFT1766

Entrez Gene IDs

116844 (Human)

Gene Symbol

LRG1

UniProt

P02750

Additional LRG1 Products

Product Documents for LRG1 Antibody (2F5.A2)

Certificate of Analysis

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Product Specific Notices for LRG1 Antibody (2F5.A2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for LRG1 Antibody (2F5.A2)

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