Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

PE/Cy7 (Excitation = 488 nm, Emission = 778 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 789211
View all LRIG1 Primary Antibodies »

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human LRIG1
Ala35-Ser779
Accession # Q96JA1

Specificity

Detects human LRIG1 in ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse LRIG1 and recombinant human LRIG3 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for LRIG1 Antibody (789211) [PE/Cy7]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer
Spectra Viewer

Flow Cytometry Panel Builder

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Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
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  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: LRIG1

LRIG1 (leucine-rich repeat and Ig-like domain-containing-1) is a 145 kDa type I transmembrane glycoprotein that shares 45 - 50% amino acid (aa) identity with two other mammalian LRIG proteins. LRIG1 shows highest expression in subsets of glial cells in brain, and certain epithelia in liver, stomach, small intestine and skeletal muscle. Within the cell, LRIG1 is expressed in the perinuclear region as well as on the surface. LRIG1 binds ErbB receptors and promotes their ubiquitination, internalization and destruction.

Long Name

Leucine-rich Repeats and Immunoglobulin-like Domains 1

Alternate Names

Img, LIG1

Gene Symbol

LRIG1

Additional LRIG1 Products

Product Documents for LRIG1 Antibody (789211) [PE/Cy7]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for LRIG1 Antibody (789211) [PE/Cy7]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

EGF Family

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