LRIG1 (leucine-rich repeat and Ig-like domain-containing-1) is a 145 kDa type I transmembrane glycoprotein that shares 45 - 50% amino acid (aa) identity with two other mammalian LRIG proteins. LRIG1 shows highest expression in subsets of glial cells in brain, and certain epithelia in liver, stomach, small intestine and skeletal muscle. Within the cell, LRIG1 is expressed in the perinuclear region as well as on the surface. LRIG1 binds ErbB receptors and promotes their ubiquitination, internalization and destruction.
LRIG1 Antibody - BSA Free
Novus Biologicals | Catalog # NBP3-18504
Scientific images may be resized, cropped, or adjusted for brightness or contrast for presentation purposes. These updates are limited to presentation and do not affect the underlying scientific interpretation of the data. Where available, additional source data may be provided upon request.
Key Product Details
Species Reactivity
Human
Applications
Western Blot, Immunoprecipitation
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
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Product Specifications
Immunogen
Recognizes region between residues Between between 1043 and 1093..
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for LRIG1 Antibody - BSA Free
Western Blot;LRIG1 Antibody[NBP3-18504]
Western Blot;LRIG1 Antibody Whole cell lysate (50 µg) from LNCaP, Hep-G2, and HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-LRIG1 antibody used for WB at 0.1 mg/ml. Detection: Chemiluminescence with an exposure time of 75 seconds.Applications for LRIG1 Antibody - BSA Free
Application
Recommended Usage
Immunoprecipitation
20-40 ug/mg lysate
Western Blot
1:2000 - 1:10000
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
Tris-citrate/phosphate pH 7 -8.
Format
BSA Free
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C. Do not freeze.
Background: LRIG1
Long Name
Leucine-rich Repeats and Immunoglobulin-like Domains 1
Alternate Names
Img, LIG1
Gene Symbol
LRIG1
Additional LRIG1 Products
Product Documents for LRIG1 Antibody - BSA Free
Certificate of Analysis
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Product Specific Notices for LRIG1 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- Immunoprecipitation Protocol
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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Associated Pathways
