High affinity 5-HT2B
receptor antagonist that displays selectivity over 5-HT2A
values are 0.75, 21.63 and 28.7 nM for 5-HT2B
receptors respectively). Orally active.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under license from Eli Lilly and company
In vivo modulation of vagal-identified dorsal medullary neurones by activation of different 5-Hydroxytryptamine2 receptors in rat.
Sevoz-Couche et al.
Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network.
Niebert et al.
PLoS One, 2011;6:e21395
LY272015, a potent, selective and orally active 5-HT2B receptor antagonist.
Cohen et al.
J.Serotonin Res., 1996;3:131
The citations listed below are publications that use Tocris products. Selected citations for LY 272015 hydrochloride include:
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