Catalog Number: 5064
Chemical Name: (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid disodium salt
Biological Activity
Sodium salt of LY 379268 (Cat. No. 2453), a highly selective group II mGlu receptor agonist.
Technical Data
  • M.Wt:
    231.11
  • Formula:
    C7H7NNa2O5
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. LY379268, a potent and selective group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal cerebral ischaemia.
    Bond et al.
    Neurosci.Lett., 1999;273:191
  2. Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanisms of action in vivo.
    Bond et al.
    J.Pharmacol.Exp.Ther., 2000;294:800
  3. (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 agonist with anxiolytic properties.
    Collado et al.
    J.Med.Chem., 2002;45:3619
Tocris Small Molecules
Description Application Cat# Citations Images  

LY 379268

2453 14  
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