Chemical Name:6-Methoxy-N-(4-methoxyphenyl)-4-quinazolinamine hydrochloride
Biological Activity Selective mGlu1 receptor antagonist (IC50 values are 143 nM and > 10 μM for mGlu1 and mGlu5 receptors respectively). Reduces hyperalgesic behavior induced by formalin in both mouse and rat with ED50 values of 28 and 16.3 mg/kg respectively.
Soluble to 20 mM in DMSO
Desiccate at RT
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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