LY 456236 hydrochloride
Chemical Name: 6-Methoxy-N-(4-methoxyphenyl)-4-quinazolinamine hydrochloride
Biological ActivitySelective mGlu1 receptor antagonist (IC50 values are 143 nM and > 10 μM for mGlu1 and mGlu5 receptors respectively). Reduces hyperalgesic behavior induced by formalin in both mouse and rat with ED50 values of 28 and 16.3 mg/kg respectively.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Anticonvulsant effects of LY456236, a selective mGlu1 receptor antagonist.
Shannon et al.
Selective blockade of metabotropic glutamate subtype mGluR1 receptors induce anti-nociceptive effects.
Bertorelli et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for LY 456236 hydrochloride
There are currently no reviews for this product. Be the first to review LY 456236 hydrochloride and earn rewards!
Have you used LY 456236 hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image