MagCellect Plus Human CD44+ Cell Isolation Kit

R&D Systems | Catalog # MAGH122

R&D Systems
Discontinued Product
MAGH122 has been discontinued. View all CD44 products.

Key Product Details

Species

Human

Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CD44

CD44 is a ubiquitously expressed receptor for hyaluronan and exerts control over cell growth, migration, and tumor progression. With variable N and O-glycosylation and splicing within the stalk, CD44 can range from 80 to 200 kDa. CD44 binds hyaluronan and other ligands within the extracellular matrix and can function as a “platform” for growth factors and metalloproteinases. It can function as a co-receptor that modifies activity of receptors including Met and the ErbB family tyrosine kinases. The intracellular domain of CD44 links the plasma membrane to the actin cytoskeleton via the ERM proteins, ezrin, radixin and moesin.

Alternate Names

CD44, ECMR-III, HCAM, HCELL, LHR, MDU2, MDU3, MIC4, MUTCH-I, Pgp1

Entrez Gene IDs

960 (Human); 12505 (Mouse); 25406 (Rat); 100126860 (Porcine)

Gene Symbol

CD44

Additional CD44 Products

Product Documents for MagCellect Plus Human CD44+ Cell Isolation Kit

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for MagCellect Plus Human CD44+ Cell Isolation Kit

For research use only

Citations for MagCellect Plus Human CD44+ Cell Isolation Kit

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FAQs for MagCellect Plus Human CD44+ Cell Isolation Kit

Showing  1 - 2 of 2 FAQs Showing All

  • Q: When using MacCellect Cell Isolation kits (MAGM*** or MAGH***), why is it important to lyse red blood cells before starting the cell isolation protocol?

    A: It is important to remove red blood cells before the isolation protocol using MagCellect isolation kits because not doing so can cause a poorer yield of selected cells. Red blood cells become sticky during the incubation protocols and may interfere with the interactions needed for removal of unwanted populations.

  • Q: Will MagCellect Plus Human CD44+ Cell Isolation Kit, catalog # MAGH122, work with mouse cells?

    A: Although we have never tested this kit with mouse cells, the CD44 antibody included in the kit has been shown to recognize both human and mouse CD44. 

  • Q: When using MacCellect Cell Isolation kits (MAGM*** or MAGH***), why is it important to lyse red blood cells before starting the cell isolation protocol?

    A: It is important to remove red blood cells before the isolation protocol using MagCellect isolation kits because not doing so can cause a poorer yield of selected cells. Red blood cells become sticky during the incubation protocols and may interfere with the interactions needed for removal of unwanted populations.

  • Q: Will MagCellect Plus Human CD44+ Cell Isolation Kit, catalog # MAGH122, work with mouse cells?

    A: Although we have never tested this kit with mouse cells, the CD44 antibody included in the kit has been shown to recognize both human and mouse CD44. 

Showing  1 - 2 of 2 FAQs Showing All
View all FAQs for Cell Selection and Detection Kits