MC3 LNP Luciferase
Tocris Bioscience | Catalog # 8889
Key Product Details
Description
Product Description
MC3 LNP Luciferase is a fully formulated lipid nanoparticle (LNP) composed of DLin-MC3-DMA (Cat. No. 7946), DSPC (Cat. No. 7943), Cholesterol (Cat. No. 7945), DMG-PEG 2000 (Cat. No. 7944) with the molar ratio 50:10:38.5:1.5 providing a convenient, ready to use, benchmark LNP formulation. Contains a reporter luciferase mRNA for in vitro and in vivo bioluminescence detection when used with D-luciferin (Cat. No. 5427).
For more information on how to prepare MC3 lipid nanoparticles for RNA delivery, please see our protocol.
Do not use a vortex to resuspend LNPs as this can disrupt the lipid membrane and damage particle integrity.
Product Specifications for MC3 LNP Luciferase
Storage
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in TBS buffer solution (10% sucrose, pH 7.5). Supplied in 200 µL aliquots, 0.05 µg/µL RNA concentration |
Calculators
Background References
References are publications that support the biological activity of the product.
- Brown Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles. Cell 2024 PMID: 39260374
Product Documents for MC3 LNP Luciferase
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for MC3 LNP Luciferase
For research use only
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