mGluR1 Antibody (5E12D8) - BSA Free

Novus Biologicals | Catalog # NBP2-61827

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 5E12D8

Format

BSA Free
View all mGluR1 Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human mGluR1 (AA: extra 387-486) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

132.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for mGluR1 Antibody (5E12D8) - BSA Free

Western Blot: mGluR1 Antibody (5E12D8)BSA Free [NBP2-61827]

Western Blot: mGluR1 Antibody (5E12D8)BSA Free [NBP2-61827]

Western Blot: mGluR1 Antibody (5E12D8) [NBP2-61827] - Analysis using GRM1 mAb against human GRM1 (AA: 387-486) recombinant protein. (Expected MW is 37.1 kDa)
Western Blot: mGluR1 Antibody (5E12D8)BSA Free [NBP2-61827]

Western Blot: mGluR1 Antibody (5E12D8)BSA Free [NBP2-61827]

Western Blot: mGluR1 Antibody (5E12D8) [NBP2-61827] - Analysis using GRM1 mAb against HEK293 (1) and GRM1 (AA: 387-486)-hIgGFc transfected HEK293 (2) cell lysate.
ELISA: mGluR1 Antibody (5E12D8) - BSA Free [NBP2-61827]

ELISA: mGluR1 Antibody (5E12D8) - BSA Free [NBP2-61827]

ELISA: mGluR1 Antibody (5E12D8) [NBP2-61827] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Applications for mGluR1 Antibody (5E12D8) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: mGluR1

This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Long Name

Metabotropic Glutamate Receptor 1

Alternate Names

GPRC1A, GRM1

Gene Symbol

GRM1

Additional mGluR1 Products

Product Documents for mGluR1 Antibody (5E12D8) - BSA Free

Certificate of Analysis

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Product Specific Notices for mGluR1 Antibody (5E12D8) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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