Mitomycin C

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3258/10
Mitomycin C | CAS No. 50-07-7 | Apoptosis Inducer Compounds
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Description: DNA cross-linking antitumor agent
Alternative Names: Ametycine

Chemical Name: [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione

Purity: ≥98%

Product Details
Citations (5)
Reviews (1)

Biological Activity

Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis. Also used for MEF/STO feeder layer preparation in stem cell culture.

Technical Data

M.Wt:
334.33
Formula:
C15H18N4O5
Solubility:
Soluble to 5 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
50-07-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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⚠ WARNING: This product can expose you to chemicals including Mitomycin C, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

Citations for Mitomycin C

The citations listed below are publications that use Tocris products. Selected citations for Mitomycin C include:

5 Citations: Showing 1 - 5

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Reviews for Mitomycin C

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itotically inactivates mouse embryonic fibroblasts (MEFs) inactivated by Mitomycin treatment
By Harry Clarke on 02/03/2019
Application: Species: Human

For studying cell cycle arrest Mitomycin has been used. MEFs have been inactivated with Mitomycin treatment.


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