Mitomycin C

  ( 3 citations )    
Product Datasheet
Catalog Number:3258
Alternate Names:Ametycine
Chemical Name:[1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Product Details
Citations (3)
Reviews
Biological Activity
Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis. Also used for MEF/STO feeder layer preparation in stem cell culture.
Technical Data
  • M.Wt:
    334.33
  • Formula:
    C15H18N4O5
  • Solubility:
    Soluble to 5 mM in water and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    50-07-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Mitomycin C include:

3 Citations: Showing 1 - 3
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  1. Elucidating Compound Mechanism of Action by Network Perturbation Analysis.
    Authors: Woo Et al.
    Cell  2015;162:441
  2. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.
    Authors: Reinhardt Et al.
    PLoS One  2013;8:e59252
  3. Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.
    Authors: Mayanagi Et al.
    J Biol Chem  2008;283:31183

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