ML 281

Catalog # Availability Size / Price Qty
4880/10
4880/50
Cat.No. 4880 - ML 281 | C22H19N3O2S | CAS No. 1404437-62-2
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Description: STK33 inhibitor

Chemical Name: N-[2-(3,4-Dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide

Purity: ≥98%

Product Details
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Biological Activity

Inhibitor of the serine/threonine kinase STK33 (IC50 = 14 nM). Exhibits >700-fold selectivity for STK33 over the structurally related protein kinase A (PKA); also exhibits 550-fold selectivity over Aurora kinase B.

Technical Data

M.Wt:
389.47
Formula:
C22H19N3O2S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1404437-62-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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