Selective MLCK inhibitor (Ki
= 0.3 μ
M). Exhibits more potent inhibition than ML 9 hydrochloride
(Cat. No. 0431) Displays reversible, ATP-competitive inhibition of Ca2+
-calmodulin-dependent and -independent smooth muscle MLCKs. Inhibits proplatelet formation and stabilization.
Soluble to 50 mM in DMSO
Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.
Saitoh et al.
Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function.
Meinders et al.
The citations listed below are publications that use Tocris products. Selected citations for ML 7 hydrochloride include:
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