AdipoR1 is a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Adiponectin induces extracellular calcium influx through AdipoR1. Binding of adiponectin to AdipoR1 results in the activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. Muscle-specific disruption of AdipoR1 suppresses the adiponectin-mediated increase in intracellular calcium concentration, and decreases the activation of CaMkk, AMPK, and SIRT1 by adiponectin.
Mouse AdipoR1 (NP_082596) VersaClone cDNA
R&D Systems | Catalog # RDC2475
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: AdipoR1
Long Name
Adiponectin Receptor 1
Alternate Names
ACDCR1, CGI45, PAQR1, TESBP1A
Gene Symbol
ADIPOR1
UniProt
Additional AdipoR1 Products
Product Documents for Mouse AdipoR1 (NP_082596) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse AdipoR1 (NP_082596) VersaClone cDNA
For research use only
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