Mouse CD38 PE-conjugated Antibody

  • Species Reactivity
  • Specificity
    Detects mouse CD38 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross‑reactivity with recombinant human CD38 is observed.
  • Source
    Polyclonal Sheep IgG
  • Purification
    Antigen Affinity-purified
  • Immunogen
    Mouse myeloma cell line NS0-derived recombinant mouse CD38
    Accession # EDL37596
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of CD38 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Sheep Anti-Mouse CD38 PE‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB4947P, filled histogram) or isotype control antibody (Catalog # IC016P, open histogram). View our protocol for Staining Membrane-associated Proteins
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD38

CD38, also known as ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase-1, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability; cyclic ADP-ribose, NAADP+, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta  cells (4, 5). CD38 has been shown to regulate oxytocin secretion, and may be involved in the development of complex social behaviors in mammals (6). Over amino acids (aa) 45-304, mouse and human CD38 share 57% aa sequence identity.

  • References:
    1. Schuber, F. and F.E. Lund (2004) Curr. Mol. Med. 4:249.
    2. Jackson, D.G. and J.I. Bell (1990) J. Immunol. 144:2811.
    3. Sun, L. et al. (1999) J. Cell Biol. 146:1161.
    4. Partida-Sanchez, S. et al. (2001) Nature Med. 7:1209.
    5. Kato, I. et al. (1995) J. Biol. Chem. 270:30045.
    6. Jin, D. et al. (2007) Nature 446:41.
  • Long Name:
    Cluster of Differentiation 38
  • Entrez Gene IDs:
    952 (Human); 12494 (Mouse); 25668 (Rat)
  • Alternate Names:
    ADP-ribosyl cyclase 1; ADP-ribosyl Cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; cADPr hydrolase 1; CD38 antigen (p45); CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC; NAD(+) nucleosidase; T10
Related Research Areas
Isotype Controls
Description Application Cat# Citations Images  

Sheep IgG PE-conjugated Antibody

Ctrl IC016P  
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Staining Reagents
Description Application Cat# Citations Images  

Flow Cytometry Staining Buffer (1X)

Flow FC001 3
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Flow Cytometry Mouse Lyse Buffer (10X)

Flow FC003 1
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Flow Cytometry Human Lyse Buffer (10X)

Flow FC002 1
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