Mouse CRELD2 Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
AF3686R-100UG

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Mouse CRELD2 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse CRELD2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human CRELD2 is observed and less than 1% cross-reactivity with recombinant mouse CRELD1 is observed
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CRELD2
Ser23-Leu350
Accession # Q9CYA0
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CRELD2

CRELD2 is a ubiquitously expressed protein that is the second member of the CRELD family of matricellular proteins. Mouse CRELD2 is synthesized as a 350 amino acid precursor protein with a signal peptide, a highly conserved domain rich in glutamic acid and tryptophan (WE), and EGF-like repeats. Human CRELD2 has been shown to interact with the alpha 4 subunit of the nicotinic acetylcholine receptor and function as a specific regulator of receptor expression. Mouse CRELD2 shares 77% amino acid sequence homology with the human CRELD2 alpha isoform.

Long Name
Cysteine-rich Protein With EGF-like Domains 2
Entrez Gene IDs
79174 (Human); 76737 (Mouse)
Alternate Names
CRELD2; cysteine-rich with EGF-like domain protein 2; cysteine-rich with EGF-like domains 2; DKFZp667O055; MGC11256

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