DSC2 belongs to the cadherin family of adhesion molecules. It is a principal component of epithelial cell desmosomes and interacts homophilically as well as heterophilically with Desmoglein-2. DSC2 is the only desmocollin that is normally expressed in simple epithelia of the GI tract, although it is downregulated during colon carcinogenesis. A variety of DSC2 mutations are associated with the cardiac arrythmia disorder ARVC.
Mouse Desmoglein-2 (NP_031909.2) VersaClone cDNA
R&D Systems | Catalog # RDC3310
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Desmocollin-2
Alternate Names
ARVD11, CDHF2, Desmocollin2, DG2, DSC2
Gene Symbol
DSC2
UniProt
Additional Desmocollin-2 Products
Product Documents for Mouse Desmoglein-2 (NP_031909.2) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse Desmoglein-2 (NP_031909.2) VersaClone cDNA
For research use only
Related Research Areas
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