Mouse GPR31 (NP_001013854) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Product Details

Mouse GPR31 (NP_001013854) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: GPR31

GPR31 is a plasma membrane G protein-coupled receptor (GPCR) that displays high affinity for 12-lipoxygenase-derived product 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-(S)-HETE). Knocking down GPR31 specifically inhibited 12-(S)-HETE-stimulated cell invasion. The diverse biological activities mediated by 12-(S)-HETE suggest that it functions as a critical signaling molecule in the regulation of physiological processes. 12-(S)-HETE/GPR31 binding leads to the activation of ERK1/2, MEK, and NF-kB.

Long Name
G-Protein-Coupled Receptor 31
Entrez Gene IDs
2853 (Human); 436440 (Mouse); 292310 (Rat)
Alternate Names
12-HETER; bA517H2.2 (G protein-coupled receptor 31); G protein-coupled receptor 31; GPR31; HETER1; probable G-protein coupled receptor 31


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