Detects mouse IFN‑ alpha / beta R2 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse (rm) IFN-gamma R2 and rmIL-20 R alpha is observed, 5% cross-reactivity with recombinant human (rh) IL-10 R beta, rmIFN-gamma RI, and rhIL-20 R beta is observed and less than 1% cross-reactivity with rhIFN-beta R alpha is observed.
Detection of IFN‑ alpha / beta R2 in A20 Mouse Cell Line by Flow Cytometry.
A20 mouse B cell lymphoma cell line was stained with Goat Anti-Mouse IFN‑ alpha / beta R2 APC‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB1083A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Background: IFN-alpha/beta R2
IFN-alpha / beta R2 belongs to the type II cytokine receptor family. It
complexes with IFN-alpha / beta R1 to form the signaling receptor complex for
the family of alpha and beta IFN subtypes. By alternative splicing, IFN-alpha / beta R2
can exist as a secreted soluble protein or as a type I membrane protein.
Interferon alpha/beta Receptor 2
Entrez Gene IDs:
3455 (Human); 15976 (Mouse)
beta receptor10; human interferon alpha; human interferon alpha/beta receptor; IFNABR; IFN-alpha binding protein; IFN-alpha/beta R2; IFN-alpha/beta receptor 2; IFN-alpha-REC; IFNAR2; IFN-aR2; IFNARB; IFNbR2; IFN-bR2; IFN-R; IFN-R-2; interferon (alpha, beta and omega) receptor 2; Interferon alpha binding protein; interferon alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; Type I interferon receptor 2
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