Mouse IFN-alpha / beta R2 Antibody Summary
Ser22-Ala239 (Lys160Asn)
Accession # Q9D1R7
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example

Limitin Inhibition of EMCV-induced Cytopathy and Neutralization by Mouse IFN‑ alpha / beta R2 Antibody. Recombinant Mouse Limitin (Catalog # 1535-LM) reduces the Encephalomyocarditis Virus (EMCV)-induced cytopathy in the L-929 mouse fibroblast cell line in a dose-dependent manner (orange line). Inhibition of EMCV activity elicited by Recombinant Mouse Limitin (30 pg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse IFN-a/ beta R2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1083). The ND50 is typically 2-10 µg/mL.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IFN-alpha/beta R2
IFN-alpha / beta R2 belongs to the type II cytokine receptor family. It complexes with IFN-alpha / beta R1 to form the signaling receptor complex for the family of alpha and beta IFN subtypes. By alternative splicing, IFN-alpha / beta R2 can exist as a secreted soluble protein or as a type I membrane protein.
Product Datasheets
Citations for Mouse IFN-alpha / beta R2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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Central nervous system regeneration is driven by microglia necroptosis and repopulation
Authors: AF Lloyd, CL Davies, RK Holloway, Y Labrak, G Ireland, D Carradori, A Dillenburg, E Borger, D Soong, JC Richardson, T Kuhlmann, A Williams, JW Pollard, A des Rieux, J Priller, VE Miron
Nat. Neurosci., 2019;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-? Production in a P2X7-Dependent Manner
Authors: C Zhang, H He, L Wang, N Zhang, H Huang, Q Xiong, Y Yan, N Wu, H Ren, H Han, M Liu, M Qian, B Du
J. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Differential Growth of IFN-beta-Engineered Tumor Cells in Nude and IFN Receptor-Null Mice.
Authors: Zhang F, Lee J, Wang D, Dong Z
J. Interferon Cytokine Res., 2006;26(2):108-18.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot
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Secondary Antibodies
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