Mouse IL-17/IL-17A (NP_034682.1) VersaClone cDNA

R&D Systems | Catalog # RDC3331

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Key Product Details

Species

Mouse

Accession Number

NP_034682.1

Background: IL-17/IL-17A

IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.

Long Name

Interleukin 17

Alternate Names

CTLA-8, CTLA8, IL-17A, IL17, IL17A

Entrez Gene IDs

3605 (Human); 16171 (Mouse); 301289 (Rat); 449530 (Porcine); 481837 (Canine); 102119976 (Cynomolgus Monkey)

Gene Symbol

IL17A

UniProt

NP_034682.1

Additional IL-17/IL-17A Products

Product Documents for Mouse IL-17/IL-17A (NP_034682.1) VersaClone cDNA

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Product Specific Notices for Mouse IL-17/IL-17A (NP_034682.1) VersaClone cDNA

For research use only

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