Mouse LAMP-1/CD107a (NP_034814.2) VersaClone cDNA

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Mouse LAMP-1/CD107a (NP_034814.2) VersaClone cDNA
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Mouse LAMP-1/CD107a (NP_034814.2) VersaClone cDNA Summary


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Background: LAMP-1/CD107a

Lysosomal associated membrane protein 1 (LAMP-1), also known as CD107a and LGP120, is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. In cytotoxic T cells and mast cells, LAMP-1 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. LAMP-1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP-1 known as M150 is expressed on the surface of activated macrophages where it promotes T cell costimulation and a Th1 biased immune response.

Long Name
Lysosome-associated Membrane Glycoprotein 1
Entrez Gene IDs
3916 (Human); 16783 (Mouse)
Alternate Names
CD107 antigen-like family member A; CD107a antigen; CD107a; LAMP1; LAMP-1; LAMPA; LGP120; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1


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