Legumain is a lysosomal cysteine protease that plays a pivotal role in the endosomal/lysosomal degradation system. Legumain deficiency causes the accumulation of pro-Cathepsins B, H and L, another group of lysosomal cysteine proteases. Overexpression of Legumain in tumors is significant for invasion/metastasis. Also known as Asparaginyl Endopeptidase, it specifically cleaves peptide bonds with Asn or Asp at the P1 position.
Mouse Legumain (NP_035305.1) VersaClone cDNA
R&D Systems | Catalog # RDC3318
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Legumain/Asparaginyl Endopeptidase
Alternate Names
AEP, Asparaginyl Endopeptidase, LGMN
Gene Symbol
LGMN
UniProt
Additional Legumain/Asparaginyl Endopeptidase Products
Product Documents for Mouse Legumain (NP_035305.1) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Mouse Legumain (NP_035305.1) VersaClone cDNA
For research use only
Related Research Areas
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