NKG2A and NKG2C are type II transmembrane proteins with extracellular C-type lectin domains. These proteins heterodimerize with CD94 to form complexes that recognize HLA-E as ligand. The NKG2A/CD94 complex delivers an inhibitory signal resulting from ITIMs within the NKG2A cytoplasmic domain. NKG2C/CD94 provides an activating signal due to association with the ITAM-containing DAP12 adapter protein. These complexes are expressed on NK and T cell subsets.
Mouse NKG2C/CD159c (NP_034783) VersaClone cDNA
R&D Systems | Catalog # RDC0814
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: NKG2C/CD159c
Long Name
Natural Killer G2C
Alternate Names
CD159c, KLRC2, NKG2-C
Gene Symbol
KLRC2
UniProt
Additional NKG2C/CD159c Products
Product Documents for Mouse NKG2C/CD159c (NP_034783) VersaClone cDNA
Product Specific Notices for Mouse NKG2C/CD159c (NP_034783) VersaClone cDNA
For research use only
Related Research Areas
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