NKG2D is a type II transmembrane protein with an extracellular C-type lectin domain. It occurs as a disulfide-linked homodimer that associates with either the DAP12 or DAP10 transmembrane adapter proteins. NKG2D is expressed on NK cells and some T cell subsets, where it functions as an activating receptor to trigger cytolytic activity and cytokine secretion. Ligands for human NKG2D include MICA, MICB, and ULBP-1, -2, -3, and -4. Mouse NKG2D ligands include H60, MULT-1, and Rae-1 alpha, beta, gamma, delta, and epsilon.
Mouse NKG2D/CD314 (NP_149069) VersaClone cDNA
R&D Systems | Catalog # RDC0851
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: NKG2D/CD314
Long Name
Natural Killer G2D
Alternate Names
CD314, D12S2489E, KLRK1
Gene Symbol
KLRK1
UniProt
Additional NKG2D/CD314 Products
Product Documents for Mouse NKG2D/CD314 (NP_149069) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse NKG2D/CD314 (NP_149069) VersaClone cDNA
For research use only
Related Research Areas
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Associated Pathways
Innate Lymphoid Cell Differentiation Pathways
