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Mouse Nogo Receptor/NgR Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB1659G Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB1659G-100UG

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Mouse Nogo Receptor/NgR Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse NgR in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human NgR.
Source
Monoclonal Rat IgG2b Clone # 202604
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse NgR
Cys27-Ser447
Accession # Q99PI8
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Nogo Receptor/NgR

NgR,also named reticulon 4 receptor, is a glycosylphosphoinositol (GPI)-anchored proteinthat belongs to the family of leucine-rich repeat proteins. NgR plays an essential role inmediating axon growth inhibition induced by the myelin-derived proteins Nogo, myelinassociatedglycoprotein (MAG), and myelin oligodendrocyte glycoprotein (Omgp). Uponligand binding, NgR associates with and activates the p75 neurotrophin receptor(p75NTR), a tumor necrosis factor superfamily member (TNFRSF16).

Long Name
Nogo-66 Receptor/Reticulon 4 Receptor
Entrez Gene IDs
65078 (Human); 65079 (Mouse)
Alternate Names
NgR; NgR1; Nogo R; Nogo receptor; Nogo-66 receptor; NogoR; NOGORUNQ330/PRO526; reticulon 4 receptor; reticulon-4 receptor; RTN4R

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